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DeCS
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Descriptor English:
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Complement Membrane Attack Complex
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Descriptor Spanish:
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complejo de ataque a la membrana del complemento
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Descriptor Portuguese:
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Complexo de Ataque à Membrana do Sistema Complemento
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Synonyms English:
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C 5b-9
C5b 8 poly C9
C5b-8-poly-C9
C5b-9
Complement Complex C5b 9
Complement Complex C5b-9
Complement Complex, Terminal
Complex, Terminal Complement
Cytolytic Terminal Complement Complex
Membrane Attack Complex
Terminal Complement Complex
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Tree Number:
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D12.776.124.486.274.930
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Definition English:
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A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC. |
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Pharmacological Action:
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Immunologic Factors
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History Note English:
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90
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Allowable Qualifiers English:
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Record Number:
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24583
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Unique Identifier:
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D015938
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Occurrence in VHL:
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Similar:
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DeCS
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